USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract

USP-NF2021 Ginkgo Biloba Extract 24% 6% Leaf Extract. We are a factory manufacturing high-quality Ginkgo Biloba Extract that meets USP-NF2021 standards.
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PRODUCTS DETAILS

Basic Info.

Model NO.
Ginkgo Biloba Extract
Product Name
Ginkgo Biloba Extract
Part Used
Leaf
Standard
Cp, USP, Ep, Water Soluble Ginkgo Biloba Extract
Extract Solvent
Ethanol & Water
Transport Package
25kgs/Fiber Drum
Specification
CP, USP, EP, Water soluble, 24%, 10: 1
Trademark
JX Nutra
Origin
China
HS Code
1302194000
Production Capacity
10mt/Month

Product Description

USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract
Product Name: Ginkgo Biloba Extract
Latin Name: Ginkgo Biloba L.
Product Type: Light Yellow or Brown-yellowPowder
Part of the Plant Used:Leaf (Dry, 100% Natural)
Extract Solvent: Ethanol & Water
Specification: CP, USP, EP, Water soluble Ginkgo Biloba Extract, 25%, 10:1USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract

Ginkgo biloba Extract specifications:
Item CP USP EP
Flavonol Glycosides ≥24% 22%~27% 22%~27%
Total Terpene Lactones ≥6% 5.4%~12% 5.4%~6.6%
Bilobalide / 2.6%~5.8% 2.6%~3.2%
Ginkgolides A+B+C / 2.8~6.2% 2.8%~3.4%
Quercetin:Kaempferol (Peak area) 0.8~1.2 0.8~1.2 0.8~1.2
Isorhamnetin: Quercetin (Peak area) >1.5 >1.5 >1.5
Ginkgolic Acid ≤10ppm ≤5ppm ≤5ppm
Free Quercetin ≤10ppm ≤5ppm ≤5ppm
Free Kaempferol  ≤10ppm ≤10ppm ≤10ppm
Free Isorhamnetin ≤4ppm ≤4ppm ≤4ppm
Rutin ≤4% ≤4% ≤4%
Solvent residue / USP<561> EC396/2005

Description of Gingko Biloba Extract:
Ginkgo Biloba Extract (GBE) refers to the effective substances extracted from Ginkgo biloba, and contains Ginkgo biloba total flavonoids, ginkgolides and other substances. It has the functions of expanding blood vessels, protecting vascular endothelial tissue, regulating blood lipids, protecting low-density lipoprotein, inhibiting PAF (platelet activating factor), inhibiting thrombosis, and scavenging free radicals.
Ginkgo biloba has a wide range of biological activities and contains a variety of chemical components, including flavonoids, terpenes, polysaccharides, phenols, organic acids, alkaloids, amino acids, steroids, trace elements, etc. Among them, vitamin C, vitamin E, carotene, calcium, phosphorus, boron, selenium and other mineral elements are also very rich, but the most important medicinal components are flavonoids and terpenes. Flavonoids and terpenes have many functions such as vasodilation and anti-oxidation.

Specification Sheet of USP44-NF39 (USP-NF2021):
Product Name: Ginkgo Biloba Extract Latin Name: Ginkgo biloba L
Part Used: Dried leaf Extract Solvent: Ethanol & water
Country Origin: China Extract Ratio: 35:1`67:1
Standard: USP44-NF39 (USP-NF2021)
                                                           
ITEM SPECIFICATION STANDARD
Appearance Brown powder Visual
Identification A: THIN-LAYER CHROMATOGRAPHIC IDENTIFICATION TEST (Test for flavanoids) 
: The Standard solution shows in its lower part with increasing R F values a yellowish-brown fluorescent zone due to rutin (R F 0.28), a light blue fluorescent zone due to chlorogenic acid (R F 0.36), and a yellow fluorescent zone due to quercetin (R F 0.92). The Sample solution shows a yellowish-brown fluorescent zone, a light blue fluorescent zone, and a yellowish-brown fluorescent zone at R F similar to those of rutin, chlorogenic acid, and quercetin, respectively, in the Standard solution. Additional yellowish to yellowish-green zones due to flavonoids detected in the Sample solution chromatogram include one zone below the rutin zone, two zones between the rutin and chlorogenic acid zones, and two zones above the chlorogenic acid zone. Other zones may be seen in the Sample solution chromatogram.
USP44-NF39
  B: HPLC (Test for content of Flavonol Glycosides): the
retention times of the peaks for quercetin, isorhamnetin,
and kaempferol of the Sample solution correspond to those of the Standard solution. In the chromatogram of the Sample solution, the ratio of the kaempferol peak to the quercetin peak is NLT 0.7, and the peak for isorhamnetin is NLT 0.1 times the size of the quercetin peak.
USP44-NF39
Loss on drying 5.0% 1g/105ºC/5hrs
Residual Solvents USP<565> USP<565>
Residual Pesticide USP<561> USP<561>
Total flavonoids (Calculated as flavonol glycosides, dry basis) 22%~27% USP44-NF39
Total terpene lactones(Dry basis) 5.4%~12% USP44-NF39
Ginkgolides A+B+C 2.8%~6.2% USP44-NF39
Bilobalide 2.6%~5.8% USP44-NF39
Rutin 4% USP44-NF39
Quercetin 0.5% USP44-NF39
Ginkgolic Acids  5ppm USP44-NF39
Total Aerobic Bacterial ≤1000CFU/g USP
Yeast &Mould ≤100CFU/g USP
Escherichia Coli Absence USP
Salmonella Absence USP


Function of Gingko Biloba Extract:
1. Expand blood vessels and protect vascular endothelial tissue
2. Regulate blood lipids
3. Protect low-density lipoprotein
5. Inhibit PAF (platelet activating factor) and inhibit thrombosis
7. Scavenging free radicals
8. Anti-hypoxia effect
9. Prevent arterial spasm

Skin care Function of Gingko Biloba Extract:
1. Whitening
When the body is not in good condition, our endocrine is easily disordered and imbalanced. At this time, there are too many oxygen free radicals in the body, but the superoxide dismutase (SOD) is insufficient, which leads to excessive oxygen free radicals and dermal layer cells to produce oxidation In response to this, a large amount of lipofuscin (lipid peroxide) is formed, causing melasma or pregnancy spots. The flavonoids contained in ginkgo biloba can hinder the formation and deposition of pigments in the dermis, whitening the skin and preventing pigmented patches. In addition to flavonoids, trace elements such as manganese and molybdenum in ginkgo leaves can also scavenge oxygen free radicals and inhibit the growth of melanin.
2. Wrinkle
It takes about 3 months for the human skin to completely renew once, but why do we still have annoying fine lines on our face? The reason is that the new cells formed in the dermis have been passed before they reach the surface of the skin. Many free radicals oxidize, and when they reach the epidermis, they already belong to aging cells. The flavonoid glycosides and flavonols in ginkgo biloba are both free radical scavengers, which can protect cells in the dermis, improve blood circulation, and prevent cells from being oxidized to produce wrinkles.

Plant Base of Ginkgo Biloba:

USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract


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Company Profile:
USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract
USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract
USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract

* Our History:
Jingxin Nutra Co., Ltd focus on the development of R&D, manufacturing and exporting of nutrition & health ingredients since 2012. Our products are widely used in the fields of nutraceutical, dietary supplements, health food, beverage, cosmetic and pharmaceutical. 

We have been proudly serving lots of contract manufacturers, brand customers and distributors in the global, and keeping very stable cooperation relationships with our customers.

* Main Market:
Europe, Russia, the Middle East, Asia, North America, South America etc. more than 50 countries and regions.



* Our Factory:
Our factory is constructed strictly in accordance with cGMP standard, it covers about 15000 square meters, with the clean workshop of 10000 square meters..
We have both production lines of plant extracts and chemicals.

-> Production lines of Plant Extracts:
We have 100,000 grade fine drying and packaging workshop to ensure that the products are not polluted.
• Extraction: It has a variety of extraction equipment, including multifunctional extraction, continuous countercurrent extraction, etc., which can be applied to the extraction of various medicinal materials, processing 8,000 tons of herb annually.
• Separation and refining: According to the product and process requirements, centrifugation, precision filtration, continuous ion exchange and other methods for separation and refining, to obtain high purity extract.
• Drying: With spray drying, freeze drying, vacuum drying, microwave drying.

-> Production lines of Chemicals:
It is based on enzyme catalysis technology to produce synthethic chemicals.The production lines are equipped with R&D center, pilot plant, chemical reaction workshop, biological fermentation workshop, clean workshop etc and meets production quality management of cGMP, FSSC22000 and HACCP.



* Main Products:
Glutathione, L-Theanine, L-Melatonin, Alpha Lipoic Acid , β-Nicotinamide mononucleotide (NMN), Coenzyme Q10, L-Carnitine Base, Selachyl alcohol, Beta Glucan, 3,3'-diindolylmethane (DIM), Ascorbic Acid (Vitamin C), Vitamin B12, Sweeteners etc.

Tongkat Ali Extract, Rutin, Fisetin, Milk Thistle Extract, Ginkgo Biloba Extract, Grape Seed Extract, Berberine HCL, Resveratrol, Monk Fruit Extract, Stevia Extract etc.

* Products Application:
Nutraceutical, dietary supplement, food additives, Beverage, cosmetics and feed additives etc.

* Certificates:
ISO, KOSHER, HALAL


* Quality Control: 
We adhere to the orientation of 'Quality first" and strictly control the whole production process meet cGMP standard.

Our quality inspection center is equipped with physical and chemical room, Ultraviolet analysis room, Atomic absorption room, Atomic fluorescence room, Gas chromatography room, High Performance Liquid Chromatography room, balance room, High greenhouse, calibration room, bacteria examination room, Reagent room, stability laboratory, sample room and central laboratory.
The main testing capabilities include loss on drying, Ash, density, TLC, solubility, optical rotation, Transmittance, heavy metals, Lead, Arsenic, Calcium, Mercury, PH, protein, amino nitrogen, Assay, Purity, Solvent residue, Pesticide residue. Microbial detection includes detection of total Plate count, coliforms, yeasts and molds, salmonella, staphylococcus aureus etc.

We strictly test all products from source to finished products to ensure it meet customer's requirements.

* Our Service:
We provide raw material ingredients, Premix blend and OEM are avaliable too.

We have decades of the experience in these fields, could offer considerate, timely and professional service.

If the quality do not complies with customer's specification, we will undertake the responsibility and give customer a full refund.

We hope to be your long-term partner for mutual benefit.
 
     
       
       
       
       
       
       
       
       
       
       
       
       

Description of Gingko Biloba Extract:
Ginkgo Biloba Extract (GBE) refers to the effective substances extracted from Ginkgo biloba, and contains Ginkgo biloba total flavonoids, ginkgolides and other substances. It has the functions of expanding blood vessels, protecting vascular endothelial tissue, regulating blood lipids, protecting low-density lipoprotein, inhibiting PAF (platelet activating factor), inhibiting thrombosis, and scavenging free radicals.
Ginkgo biloba has a wide range of biological activities and contains a variety of chemical components, including flavonoids, terpenes, polysaccharides, phenols, organic acids, alkaloids, amino acids, steroids, trace elements, etc. Among them, vitamin C, vitamin E, carotene, calcium, phosphorus, boron, selenium and other mineral elements are also very rich, but the most important medicinal components are flavonoids and terpenes. Flavonoids and terpenes have many functions such as vasodilation and anti-oxidation.
USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract
Specification Sheet of USP:
Item  Specification
(Appearance)
(Color)
(Odor & Taste)
Fine powder
Brown yellow to Brown
Bitterness
(Identification) Meet the standard
(Total Flavones Glycoside)
  (Quercetin Glycoside)
  (Kaempferol Glycoside)
  (Isorhamnetin Glycoside)
22%-27%


 
(Total Terpence Lactones)
  A(Lactones A)
  B(Lactones B)
  C(Lactones C)
  (Bilobalides)
5.4%-12.0%



2.6%-5.8%
Quercetin: Kaempferol (peak area) 0.8~1.2
Isorhamnetin:Quercetin (peak area) >0.15
(Ginkgolic Acid) ≤5.0 PPM
Free Quercetin ≤5mg/g
Free Kaempferol ≤10mg/g
Free Isorhamnetin ≤4mg/g
(Loss on Drying) ≤5.0%
(Residue on Ignition) ≤0.8%
(Heavy Metals)
  (Pb)
  (As)
  (Hg)
  (Cd)
≤10ppm
≤2.0ppm
≤2.0ppm
≤0.1ppm
≤1.0ppm
(Microbiological)
  (Total Plate Count)
  (Yeast & Mold)
  (E. Coli)
  (Salmonella)
  (Staphylococcus)

<1000cfu/g Max
<100cfu/g Max
(Negative)
(Negative)
(Negative)



Function of Gingko Biloba Extract:
1. Expand blood vessels and protect vascular endothelial tissue
2. Regulate blood lipids
3. Protect low-density lipoprotein
5. Inhibit PAF (platelet activating factor) and inhibit thrombosis
7. Scavenging free radicals
8. Anti-hypoxia effect
9. Prevent arterial spasm

Skin care Function of Gingko Biloba Extract:
1. Whitening
When the body is not in good condition, our endocrine is easily disordered and imbalanced. At this time, there are too many oxygen free radicals in the body, but the superoxide dismutase (SOD) is insufficient, which leads to excessive oxygen free radicals and dermal layer cells to produce oxidation In response to this, a large amount of lipofuscin (lipid peroxide) is formed, causing melasma or pregnancy spots. The flavonoids contained in ginkgo biloba can hinder the formation and deposition of pigments in the dermis, whitening the skin and preventing pigmented patches. In addition to flavonoids, trace elements such as manganese and molybdenum in ginkgo leaves can also scavenge oxygen free radicals and inhibit the growth of melanin.
2. Wrinkle
It takes about 3 months for the human skin to completely renew once, but why do we still have annoying fine lines on our face? The reason is that the new cells formed in the dermis have been passed before they reach the surface of the skin. Many free radicals oxidize, and when they reach the epidermis, they already belong to aging cells. The flavonoid glycosides and flavonols in ginkgo biloba are both free radical scavengers, which can protect cells in the dermis, improve blood circulation, and prevent cells from being oxidized to produce wrinkles.

Plant Base of Ginkgo Biloba:

USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract
Company Profile:

USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract
USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract
USP-NF2021 (USP44) Ginkgo Biloba Extract 24% 6% Ginkgo Biloba Leaf Extract

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